Hemophilia is a genetic disorder caused due to a mutation in the genes. This disorder can be inherited or can be the result of a new mutation. Hemophilia is more prevalent in men than women, since it is an X-linked recessive trait. The defected X chromosome is deficient in blood clotting protein, which disables the blood from thickening and coagulating during an injury, bruise or trauma.
To further understand the reason of why hemophilia in women is a rarity, we would have to know about the XX chromosomes and the XY chromosomes. There are 24 pairs of chromosomes in humans. Out of which one... Read More
Severe hemophilia is characterised by clotting factor activity being below 1%. Normal clotting factor activity is usually above 50%. The low level of clotting factor delays clotting which can be fatal and thus requires extra precautions and care.
Individuals with hemophilia have been known to bleed profusely and for a prolonged period. Soft tissues and areas with thin fibrin are more prone to such bleeds and allow easy injuries. Bleeding in joints, followed by an inflammation is another sign of hemophilia. Such internal haemorrhages can lead to permanent deformities. Site of an internal... Read More
Hemophilia is a genetic bleeding disorder where the blood of the patient does not clot during an injury or trauma. This is due to a deficiency or absence of blood clotting protein in the blood. There are twelve clotting factors in the human body. Two blood clotting proteins, a deficiency in either causes hemophilia are factor VIII and factor IX. A deficiency in factor VIII results in hemophilia A while that of factor IX results in Hemophilia B.
Since no permanent cure for hemophilia is available patients have to undergo regular infusions which are painful, expensive and if the infusion is... Read More
Just like any other disease, hemophilia too comes with certain cares and precautions that need to be taken. Instead of allowing hemophilia to take the zest away from your life, you should try to conquer it with your family.
Living with hemophilia has been made considerably easier with new therapies and technologies. With new medication and therapies the life expectancy of hemophilia patients has leaped from 13 years of age to 50+ years of age. Such advancements have been noticed around the world. This is indicative of the medical solutions that are available for the treatment of hemophilia.... Read More
Hemophilia is a disorder in the genes of any individual. To answer is hemophilia genetic, one has to understand the two ways through which the disease can be acquired:
Either by inheritance
Or by a de novo mutation of the genes.
Is hemophilia genetic and its genetic significance can also be ascertained by its hereditary nature. Humans have 23 pairs of chromosomes. Out of which, one pair of chromosome is responsible for determining the sex of an individual, these are called sex chromosomes. While men have a combination of XY chromosomes, females are XX. Patients suffering from hemophilia... Read More
Being diagnosed with hemophilia can change your lifestyle overnight. No more active sports and no more of casual tussles with friends. Life of a hemophilia patient can sometimes be challenging but it should not discourage your spirits to overcome it.
Immediate effects of hemophilia can include bleeding due to minor injuries and bleeding into joints. Soft tissues and areas with thin fibrin are more prone to such bleeds and allow easy injuries. Bleeding in joints, followed by an inflammation is another sign of hemophilia. Such internal hemorrhages can lead to permanent deformities. Site of an... Read More
Hemophilia is a genetic disorder caused due to a mutation in the genes. This disorder can be inherited or can be the result of a new mutation. Hemophilia is more prevalent in men than women, since it is an X-linked recessive trait. It affects approximately 1 male in 5000. . Although statistics for the count of hemophilia in men have been tracked and documented, there are no conclusive statistics which reveal the number of women who have been affected with it.
In people suffering from hemophilia, the chromosomes are deficient in blood clotting protein, which disables the blood from thickening... Read More
The severity of hemophilia is decided with respect to the activity of clotting factor in the blood. When clotting factor activity lies in the range of 5% to 40% it is termed as mild hemophilia. These can be ascertained with the help of clotting factor activity tests of the blood and the time the blood takes to clot.
Mild hemophilia is generally diagnosed later in life, in event of a surgery where the bleeding does not stop or in case of a minor dentistry which leads to emergency room complications. Apart from such external traumas, it is difficult to diagnosis mild hemophilia and many cases... Read More
Hemophilia bleeding disorder is an X- linked recessive trait. This means that for the disorder to surface in a child, both the X chromosomes of a girl child has to carry the trait. On the other hand for a boy child to have the disorder, he must inherit the defective X chromosome from either parent, since men have only one X chromosome.
Hemophilia bleeding has been a much talked about topic since time immemorial. Ancient scholars and learned men alike have spoke of the various hazards associated with it. The first written record which can be linked to hemophilia is the writings of the Jews of... Read More
For people with hemophilia, life can be a challenge. However, the word hemophilia should not be associated with terror. It depends upon the severity of hemophilia that you are affected with. The severity of hemophilia bleeding depends upon the extent of deficiency of factor VIII. The normal percentage of factor VIII activity in the blood should lie above 50%, whereas in cases of mild hemophilia, it would lie within the range of 5% to 50%. When the range is above 1% but below 5%, it is classified as moderate hemophilia. A person suffering from severe hemophilia has a factor activity of less... Read More